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Compound Profile

5-Amino-1MQ (NNMT Inhibitor): Research Profile

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule research compound studied as an inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT).

Research background

NNMT is an enzyme involved in cellular methylation and NAD+ metabolism. 5-Amino-1MQ is used as a tool compound to probe NNMT activity in cell-culture research, particularly in adipocyte and metabolic models.

Reported activity in research models

In cell-based research models, 5-Amino-1MQ has been investigated for NNMT enzyme inhibition and downstream effects on cellular NAD+ and methylation pathways. These observations are limited to laboratory and preclinical research settings and are not statements about outcomes in humans.

Handling and storage

Supplied as a lyophilized powder. Store lyophilized material at -20°C. Reconstitution with bacteriostatic or sterile water is common for laboratory handling; keep any reconstituted solution refrigerated and use it within the timeframe appropriate to the researcher’s protocol.

Analytical and COA

Purity is determined by HPLC and identity is confirmed by mass spectrometry. Each batch ships with a batch-specific certificate of analysis from an independent third-party laboratory; refer to the COA for lot-specific measured values. Endotoxin and sterility testing are not performed unless explicitly stated.

View the 5-Amino-1MQ product page and batch COA →
📚 See the latest 5-Amino-1MQ studies on PubMed →Live results from the U.S. National Library of Medicine, sorted newest first.
Research use only. All compounds are sold strictly for in-vitro laboratory research. Not for human or veterinary use, consumption, or diagnostic application. Nothing here is medical advice or a claim of safety or efficacy.

Frequently asked questions

What is 5-Amino-1MQ?

5-Amino-1MQ is a small-molecule NNMT enzyme inhibitor used as a tool compound in cellular metabolic-regulation laboratory research.

How should 5-Amino-1MQ be stored?

Store the material at -20°C. Handle and store any reconstituted or dissolved solution per your laboratory protocol.

What does the COA report?

Purity by HPLC and identity by mass spectrometry, batch-specific, from an independent third-party lab. Refer to the COA for the measured purity. Endotoxin and sterility are not tested unless stated.

Is 5-Amino-1MQ for human use?

No. It is sold strictly for in-vitro laboratory research and is not for human or veterinary use.

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