KPV is a tripeptide (Lys-Pro-Val) corresponding to the C-terminal sequence of alpha-melanocyte-stimulating hormone (alpha-MSH). It is studied as a reference compound in inflammation and mucosal-biology research.
The KPV sequence retains anti-inflammatory signaling activity associated with alpha-MSH while lacking its pigmentary sequence. Its small size and stability make it a common tool compound in cell-culture and rodent models.
In vitro and in animal studies, KPV has been investigated for its effects on NF-κB signaling, pro-inflammatory cytokine expression, and intestinal-epithelium research models. These observations are limited to laboratory and preclinical research settings and are not statements about outcomes in humans.
Supplied as a lyophilized powder. Store lyophilized material at -20°C. Reconstitution with bacteriostatic or sterile water is common for laboratory handling; keep any reconstituted solution refrigerated and use it within the timeframe appropriate to the researcher’s protocol.
For synthetic research peptides, purity is determined by HPLC and identity is confirmed by mass spectrometry. Independent third-party testing is expanding across the catalog, and each certificate of analysis is published on the product page it covers as results come back. Refer to that certificate for the testing laboratory, the methods run, and the measured values. Endotoxin and sterility testing are not performed unless explicitly stated.
KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-MSH, used as a reference compound in inflammation and mucosal-biology laboratory research.
Store the lyophilized powder at -20°C. Handle and store any reconstituted solution per your laboratory protocol.
For synthetic research peptides, purity is determined by HPLC and identity by mass spectrometry. Independent third-party testing is expanding across the catalog, and each certificate of analysis is published on the product page it covers as results come back. Refer to that certificate for the testing laboratory, the methods run, and the measured values. Endotoxin and sterility are not tested unless stated.
No. It is sold strictly for in-vitro laboratory research and is not for human or veterinary use.