BANANA PEPPERS LLC
Compound Profile

MOTS-c (Mitochondrial-Derived Peptide): Research Profile

MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. It is used as a reference compound in metabolic-signaling research.

Research background

As one of a small group of mitochondrial-derived peptides, MOTS-c is a tool compound for studying communication between mitochondria and the cell nucleus in preclinical models.

Reported activity in research models

In cell and rodent models, MOTS-c has been investigated in the context of AMPK-pathway signaling, glucose-utilization research, and metabolic-stress adaptation. These observations are limited to laboratory and preclinical research settings and are not statements about outcomes in humans.

Handling and storage

Supplied as a lyophilized powder. Store lyophilized material at -20°C. Reconstitution with bacteriostatic or sterile water is common for laboratory handling; keep any reconstituted solution refrigerated and use it within the timeframe appropriate to the researcher’s protocol.

Analytical and COA

For synthetic research peptides, purity is determined by HPLC and identity is confirmed by mass spectrometry. Independent third-party testing is expanding across the catalog, and each certificate of analysis is published on the product page it covers as results come back. Refer to that certificate for the testing laboratory, the methods run, and the measured values. Endotoxin and sterility testing are not performed unless explicitly stated.

📚 See the latest MOTS-c studies on PubMed →Live results from the U.S. National Library of Medicine, sorted newest first.
Research use only. All compounds are sold strictly for in-vitro laboratory research. Not for human or veterinary use, consumption, or diagnostic application. Nothing here is medical advice or a claim of safety or efficacy.

Frequently asked questions

What is MOTS-c?

MOTS-c is a mitochondrial-derived peptide used as a reference compound in metabolic-signaling and AMPK-pathway laboratory research.

How should MOTS-c be stored?

Store the lyophilized powder at -20°C. Handle and store any reconstituted solution per your laboratory protocol.

What does a published COA report?

For synthetic research peptides, purity is determined by HPLC and identity by mass spectrometry. Independent third-party testing is expanding across the catalog, and each certificate of analysis is published on the product page it covers as results come back. Refer to that certificate for the testing laboratory, the methods run, and the measured values. Endotoxin and sterility are not tested unless stated.

Is MOTS-c for human use?

No. It is sold strictly for in-vitro laboratory research and is not for human or veterinary use.

Browse the catalog →